By Joseph Panno
Gr. 9-12. The technology and expertise are distinctive, dense, exact, and updated during this name within the New Biology sequence, and the readable dialogue of the moral concerns indicates that there aren't any uncomplicated solutions. Physiologist Panno explains how stem cells can be utilized to regard, and doubtless therapy, a large choice of illnesses, and he predicts that using grownup stem cells will quickly be regimen. a major bankruptcy appears at felony practices within the united states, Europe, and the U.K. The e-book contains occasional diagrams; an in depth, precise word list; and plenty of bibliographical references to technological know-how and moral discussions in print and on the internet. additionally, there's a bankruptcy summarizing telephone biology and recombinant DNA know-how. a delicately performed, in-depth sequence that would paintings good for researchers and debaters, adults in addition to youth. different titles during this new sequence: The mobilephone, getting older, Animal Cloning, melanoma, and Gene remedy. Hazel Rochman Copyright © American Library organization. All rights reserved
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Gr. 9-12. The technology and know-how are distinctive, dense, actual, and updated during this identify within the New Biology sequence, and the readable dialogue of the moral matters indicates that there are not any basic solutions. Physiologist Panno explains how stem cells can be utilized to regard, and doubtless remedy, a wide selection of illnesses, and he predicts that using grownup stem cells will quickly be regimen.
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Additional info for Stem Cell Research: Medical Applications And Ethical Controversy (The New Biology)
Selecting growth factors for these experiments is an example of educated guesswork. If the intention of the experiment is to produce neurons or epithelial cells, the scientists involved will select growth factors such as Human Stem Cells 25 epidermal growth factor (EGF) and nerve growth factor (NGF), both of which are known to influence the proliferation of these cells in vivo. Other growth factors, such as transforming growth factor (TGF) or the DIRECTED DIFFERENTIATION OF HUMAN STEM CELLS Source Conditions Resulting Cell Types Adult bone marrow Injection into mice Hepatocytes Red blood cells White blood cells Adult bone marrow Epithelial growth factor (EGF) Neurotrophic growth factor Cultured with fetal rat neurons Neurons Adult bone marrow Transforming growth factor (TGF) Fetal bovine serum Insulin Adipocyte TGF EGF Cardiomyocyte NGF Fibroblast growth factor (FGF) Bone morphogenic protein (BMP) Hepatocyte growth factor (HGF) Retinoic acid Neuron Embryo (H9 cell line) Embryo (H9 cell line) Injection into mice Leukemia inhibitory factor Chondrocyte Osteocyte Blood cell Precursor Liver Pancreas Muscle Bone Cartilage Gut epithelia Neural epithelia Smooth muscle Striated muscle 26 Stem Cell Research hormone insulin, are known to influence tissues derived from the mesoderm, such as muscle and cartilage.
Protein kinase receptors consist of a single polypeptide chain that spans the cell membrane, with the portion inside the cell containing the enzymatic region. The kinase region of the growth factor receptor adds a phosphate group specifically to the amino acid tyrosine. Other protein kinases specialize in adding phosphate groups to serine or threonine amino acid residues. Human Stem Cells 29 Protein growth factors bind to their receptor as dimers. That is, two growth factor molecules join together to form an activated pair that is capable of binding to the receptor.
Chronic leukemia progresses much more slowly, and even though the leukocytes are transforming, they retain some of their normal functions, so the immune system is not destroyed so quickly or so completely. The standard treatment for leukemia involves radiation and chemotherapy, which kill the cancerous cells. Extreme forms of this therapy involve the complete destruction of the bone marrow with radiation therapy, after which the patient receives new bone marrow from a suitable donor. The great problem associated with this therapy is the often-impossible task of finding a donor.
Stem Cell Research: Medical Applications And Ethical Controversy (The New Biology) by Joseph Panno