Get Amniotic Membrane: Origin, Characterization and Medical PDF

By Ana Catarina Mamede, Maria Filomena Botelho

ISBN-10: 9401799741

ISBN-13: 9789401799744

ISBN-10: 940179975X

ISBN-13: 9789401799751

This e-book describes the human amniotic membrane from its foundation, characterization and clinical purposes, summarizing the entire most up-to-date advancements and findings relating to this tissue with contributions from the various best researchers within the box. The e-book addresses concerns for its upkeep, separation and identity of amniotic membrane-derived cells, in addition to the aptitude moral matters inquisitive about their use. the subject of this publication is very pertinent for clinicians and researchers inquisitive about the study and use of this tissue.

Show description

Read or Download Amniotic Membrane: Origin, Characterization and Medical Applications PDF

Similar cell biology books

New PDF release: Stem Cell Research: Medical Applications And Ethical

Gr. 9-12. The technological know-how and know-how are targeted, dense, actual, and updated during this name within the New Biology sequence, and the readable dialogue of the moral concerns exhibits that there are not any easy solutions. Physiologist Panno explains how stem cells can be utilized to regard, and probably medication, a large choice of ailments, and he predicts that using grownup stem cells will quickly be regimen.

Read e-book online Biomembranes Part S PDF

The significantly acclaimed laboratory typical, equipment in Enzymology, is likely one of the so much hugely revered guides within the box of biochemistry. for the reason that 1955, each one quantity has been eagerly awaited, often consulted, and praised by way of researchers and reviewers alike. The sequence comprises a lot fabric nonetheless proper this present day - actually a vital ebook for researchers in all fields of existence sciences

RNA Structure and Folding: Biophysical Techniques and by Dagmar Klostermeier, Christian Hammann PDF

Whereas structure-function relationships of proteins were studied for a very long time, structural stories of RNA face extra demanding situations. however, with the continual discovery of novel RNA molecules with key mobile capabilities and of novel pathways and interplay networks, the necessity for structural details of RNA remains to be expanding.

Download PDF by Donald Armstrong: Advanced Protocols in Oxidative Stress III

Complicated Protocols in Oxidative tension III keeps the thread of the 1st books through protecting know-how starting from a conveyable hand held detector for distant research of antioxidant means to stylish know-how akin to shotgun lipidomics, mitochondrial imaging, nano sensors, fluorescent probes, chromatographic fingerprints, computational versions and bio statistical purposes.

Extra resources for Amniotic Membrane: Origin, Characterization and Medical Applications

Example text

The amniotic membrane contains various tissue inhibitors (TIMP-1, -2, -3, -4) of MMPs [61]. They regulate many crucial processes in inflammation and fibrotic processes including chemotactic migration of inflammatory cells, mitosis of fibroblasts, and synthesis and degradation of extracellular components [16]. IL-1 receptor agonist and IL-10 are potent anti-inflammatory cytokines that are expressed by amniotic membrane [3]. IL-10 counteracts the action of different pro-inflammatory cytokines, such as IL-6, IL-1, IL-8 and tumor necrosis factor (TNF) [62].

The outer layer, the chorion, consists of trophoblastic chorionic and mesenchymal tissues. The inner layer, the amniotic membrane, consists of a single layer of ectoderm-derived epithelium uniformly arranged on the basement membrane, which is one of the thickest membranes found in any human tissue, and a collagenrich mesenchymal layer [24]. This mesenchymal layer can be subdivided into the compact layer forming the main fibrous skeleton of the amniotic membrane, the fibroblast layer and an intermediate layer, which is also called the spongy layer or zona spongiosa [16, 19].

Fetal fibronectin is a protein that acts as a “glue” during pregnancy attaching the amniotic sac, due to their multiple binding domains for cells, as well as other matrix components, which stabilize the whole system of cells and matrix [46]. This is accomplished by specialized domains, of at least six peptide sites capable of mediating cell adhesion. Most cells can adhere to fibronectin through its centrally located cell-binding domain, the Arg-Gly-Asp (RGD) sequence is crucial for this. There are six different cell surface receptors or integrin receptors which recognize this site, but the conformation of the fibronectin is also important for the specificity and affinity of this cell-fibronectin recognition [45].

Download PDF sample

Amniotic Membrane: Origin, Characterization and Medical Applications by Ana Catarina Mamede, Maria Filomena Botelho


by Robert
4.3

Rated 4.68 of 5 – based on 46 votes